Z700002 Chemical Structure

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Product Description

Catalogue NumberZ700002
Chemical NameZonisamide-d4
Synonyms1,2-(Benzisoxazole-d4)-3-methanesulfonamide; 3-(Sulfamoylmethyl)-1,2-benzisoxazole-d4; AD 810-d4; Aleviatin-d4; Excegran-d4; PD 110843-d4; Zonegran-d4;
CAS Number1020720-04-0
Alternate CAS #68291-97-4 unlabelled
Molecular FormulaC8H4D4N2O3S
AppearanceWhite to Light Brown Solid
Melting Point162-165°C
Molecular Weight216.25
Storage-20°C Freezer, Under Inert Atmosphere
SolubilityDMSO (Slightly), Methanol (Slightly)
Category Standards; Isotopic Labeled Analogues; Neurochemicals; Pharmaceutical/API Drug Impurities/Metabolites;
ApplicationsLabelled sulfonamide antiseizure agent; blocks repetitive firing of voltagesensitive sodium channels and reduces voltage-sensitive T-type calcium currents. Heterocyclic methanesulfonide with anticonvulsant properties. The compound is under investigation for potential therapeutic use as an antiepileptic drug. Anticonvulsant.
ReferencesMasuda, Y., et al.: Arzneim.-Forsch., 30, 477 (1980), Hammond, E.J., et al.: Gen. Pharmacol., 18, 303 (1987), Schmidt, D., et al.: Epilepsy Res., 15, 67 (1993), Sorkin, E.M., et al.: Drugs, 45, 760 (1993),