
All Products are stable to be shipped at room temperature, unless otherwise specified.
Pack Size | Quantity | Price (USD) | Sub Total |
---|---|---|---|
2.5mg | $ 55.00 | 0.0 | |
5mg | $ 80.00 | 0.0 | |
25mg | $ 230.00 | 0.0 | |
250mg | $ 1130.00 | 0.0 | |
Exact Weight Packaging | $ 145.00 | 0.0 | |
Total | $ 0.0 |
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Z623505
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Product Description
Catalogue Number | Z623505 |
Chemical Name | Zoledronic acid |
Synonyms | P,P'-[1-Hydroxy-2-(1H-imidazol-1-yl)ethylidene]bis-phosphonic Acid; |
CAS Number | 118072-93-8 |
Molecular Formula | C₅H₁₀N₂O₇P₂ |
Appearance | White to Off-White Solid |
Melting Point | >210°C (Subl.) |
Molecular Weight | 272.09 |
Storage | 4°C, Hygroscopic |
Solubility | Water (Slightly) |
Stability | extremely hygroscopic, Extremely Hygroscopic |
Category | Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; |
Applications | Zoledronic acid induces apoptosis in osteoclasts by inhibiting enzymes of the mevalonate pathway and preventing the isoprenylation of small GTP-binding proteins such as Ras and Rho. |
References | Jagdev, S., et al.: Br. J. Cancer, 84, 1126 (2001); Viereck, V., et al.: Biochem. Biophys. Res. Commun., 291, 680-686.Croucher. P., et al.: J. Bone Miner. Res., 2003, 18(3), 482-492. |