Z587002 Chemical Structure

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$ 205.000.0
$ 1620.000.0
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$ 145.000.0
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Product Description

Catalogue NumberZ587002
Chemical NameZofenopril-d5 Calcium Salt
Synonyms[1(S),4(S)]-1-(3-Mercapto-2-methyl-1-oxopropyl)-4-phenyl-thio-L-proline-S-benzoyl-d5 Ester Calcium Salt; Bifril-d5; Zofenil-d5;
Alternate CAS #unlabelled: 81938-43-4
Molecular FormulaC₄₄H₃₄D₁₀CaN₂O₈S₄
AppearanceOff-White to Light Yellow Crystalline Solid
Melting Point>250°C
Molecular Weight907.23
Category Standards; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
ApplicationsAngiotensin-converting enzyme ACE inhibitor. A prodrug that is de-esterified to the active inhibitor, the sulfhydryl group containing metabolite, Zofenoprilat.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
ReferencesGorren, A., et al.: Biochem. J., 331, 801 (1998), Subissi, A., et al.: Cardivascular Drug Reviews, 17, 2 (1999), Marchand, C., et al.: Mol. Pharmacol., 64, 600 (2003), Maurin, C., et al.: J. Med. Chem., 47, 5583 (2004),