Z486502 Chemical Structure

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1mg
$ 245.000.0
2.5mg
$ 525.000.0
5mg
$ 1005.000.0
10mg
$ 1910.000.0
Exact Weight Packaging
$ 145.000.0
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Z486502

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Product Description

Catalogue NumberZ486502
Chemical NameZM 213689-d6 Disodium Salt (Meropenem Impurity) (Mixture of double bond isomers)
Synonyms(αS,2S,3R,4S)-5-Carboxy-4-[[(3S,5S)-5-[(dimethylamino)carbonyl]-3-pyrrolidinyl]thio]-3,4-dihydro-α-[(1R)-hydroxyethyl]-3-methyl-2H-pyrrole-2-acetic Acid-d6 Disodium Salt; H 4295-d6 Disodium Salt; ICI 213689-d6 Disodium Salt; UK 1a-d6 Disodium Salt;
Alternate CAS #unlabelled: Z486500
Molecular FormulaC34H38D12N6Na4O12S2
Molecular Weight902.96
Category Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
ApplicationsZM 213689-d6 Disodium Salt is a labelled form of ZM 213689 Disodium Salt which is a major metabolite of Meropenem (M225620) - a carbapenem antibiotic - in plasma and urine. This metabolite existed as a mixture of 1-pyrroline and its 2-pyrroline isomer, and the coexistence of the two isomers at equilibrium in aqueous solutions was observed by NMR.
ReferencesTakeuchi, Y., et al.: J. Antibiotics, 46, 827 (1993), Wiseman, L., et al.: Drugs, 50, 73 (1995), Valtonen, M., et al.: J. Antimicrob. Chemother., 45, 701 (2000),