Zaprinast


Catalogue Number: Z150000
Chemical Name: Zaprinast
Synonyms: 3,6-dihydro-5-(2-propoxyphenyl)-7H-1,2,3-triazolo[4,5-d]pyrimidin-7-one; 1,4-Dihydro-5-[2-propoxyphenyl]-7H-1,2,3-triazolo[4,5-d]pyrimidine-7-one; 8-Aza-2-(2-propoxyphenyl)-6-purinone; M&B 22,948;
CAS Number: 37762-06-4
Molecular Formula: C₁₃H₁₃N₅O₂
Appearance: Pale Pink to Pale Red Solid
Melting Point: 229-233°C (dec.)
Molecular Weight: 271.3
Storage: -20˚C Freezer
Solubility: DMSO (Slightly), Methanol (Slightly, Heated)
Category: Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals,
Applications: A selective inhibitor of cyclic-GMP phosphodiesterase (PDE V, calmodulin insensitive). Since cGMP mediates the vasorelaxant action of nitric oxide, as well as the natriuretic and diuretic effect of atrial natriuretic factor (ANF) through the activation of PKG (cGMP dependent protein kinase), such inhibitors may display vasodilating, relaxant, and diuretic effects. These compounds may prove useful in treating hypertension and congestive heart failure.
References:

All Products are stable to be shipped at room temperature, unless otherwise specified.
MSDS: Z150000.pdf
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  Pack size Price(USD)
10mg $45.00
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50mg $80.00
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500mg $495.00
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25mg $60.00
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100mg $110.00
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1g $880.00
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Exact Weight Packaging ($75(USD) / Vial)
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Inventory Status:   In Stock




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