U700835 Chemical Structure

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100mg
$ 140.000.0
250mg
$ 345.000.0
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U700835

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Product Description

Catalogue NumberU700835
Chemical NameUlixertinib Hydrochloride
Synonyms4-(5-Chloro-2-(isopropylamino)pyridin-4-yl)-N-((S)-1-(3-chlorophenyl)-2-hydroxyethyl)-1H-pyrrole-2-carboxamide Hydrochloride
CAS Number1956366-10-1
Alternate CAS #Free form 869886-67-9
Molecular FormulaC₂₁H₂₂Cl₂N₄O₂ + (HCl)
AppearanceWhite to Off-White Solid
Melting Point231-232°C
Molecular Weight433.33 + (36.46)
Storage-20°C Freezer
SolubilityDMSO (Slightly), Methanol (Slightly)
Category Standards; Pharmaceutical/API Drug Impurities/Metabolites;
ApplicationsUlixertinib Hydrochloride is an acid salt of Ulixertinib (U700830), a potent and reversible ERK1/ERK2 inhibitor with IC50 of <0.3 nM for ERK2. Inhibits cell proliferation. Anti-cancer.
ReferencesWard, R. et al.: J. Med. Chem., 58, 4790 (2015);