T795550 Chemical Structure

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T795550

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Product Description

Catalogue NumberT795550
Chemical Name5-Triisopropylsilyl-ethynyl (S)-(-)-Nicotine
Synonyms3-[(2S)-1-Methyl-2-pyrrolidinyl]-5-[2-[tris(1-methylethyl)silyl]ethynyl]-pyridine
CAS Number916046-39-4
Molecular FormulaC21H34N2Si
AppearanceYellow Oil
Molecular Weight342.59
Storage-20°C Freezer
SolubilityChloroform, Dichloromethane, Ethyl Acetae
Category Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites; Nicotine Derivatives and Metabolites;
ApplicationsProtected 5-Ethynyl Nicotine (E932200), an intermediate of nicotinic acetylcholine receptor agonist SIB-1508Y.
ReferencesPillon, B., et al.: Neurology, 39, 762 (1989), Schneider, J., et al.: Brain Res., 519, 122 (1990), Cosford, N., et al.: J. Med. Chem., 39, 3235 (1996), Sacaan, A., et al.: J. Pharmacol. Exp. Ther., 280, 373 (1997)