T795445 Chemical Structure

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Product Description

Catalogue NumberT795445
Chemical Name(+)-Trimethaphan Camphorsulfonate
SynonymsOctahydro-2-oxo-1,3-bis(phenylmethyl)-thieno[1',2':1,2]thieno[3,4-d]imidazol-5-ium (1S,4R)-7,7-Dimethyl-2-oxobicyclo[2.2.1]heptane-1-methanesulfonate; Decahydro-2-oxo-1,3-bis(phenylmethyl)-thieno[1',2':1,2]thieno[3,4-d]imidazol-5-ium Salt with (1S)-7,7-Dimethyl-2-oxobicyclo[2.2.1]heptane-1-methanesulfonic Acid; Trimethaphan, Camphorsulfonate; β-camphorsulfonate; Arfonad; Arphonad; Methioplegium; Nu 2222; Ro 2-2222; Trimetaphan Camphorsulfonate; Trimetaphan Camsilate; Trimetaphan Camsylate; Trimethaphan 10-Camphorsulfonate; Trimethaphan Camsylate
CAS Number87335-42-0
Molecular FormulaC₃₂H₄₁N₂O₅S₂⁺
Molecular Weight597.81
Category Standards; Pharmaceutical/API Drug Impurities/Metabolites;
Applications(+)-Trimethaphan Camphorsulfonate is a derivative of biotin (389040). Trimethaphan is used as a ganglionic blocker in hypertension. Growth factor present in minute amounts in every living cell. Plays an indispensable role in numerous naturally occurring carboxylation reactions. Occurs mainly bound to proteins or polypeptides. The richest sources are liver, kidney, pancreas, yeast, and milk. The biotin content of cancerous tumors is higher than that of normal tissue.
Referencesdu Vigneaud, et al.: J. Biol. Chem., 146, 475 (1942), Traub, et al.: Nature, 178, 649 (1956), Siegel, H., et al.: Experienta, 37, 789 (1981), Vesely, D.L., Science, 216, 1329 (1982), Hugues, M., et al.: Biochemistry, 31, 12 (1992); Nakamura, K., et al. Anaesthesia, 35, 1202 (1980)