7-O-(Triethylsilyl)-2’-O-tert-butyl(dimethyl)silyl Paclitaxel

Catalogue number: T777810
Chemical name: 7-O-(Triethylsilyl)-2’-O-tert-butyl(dimethyl)silyl Paclitaxel
Synonyms: (αR,βS)-β-(Benzoylamino)-α-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-4-[(triethylsilyl)oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl Ester; Paclitaxel - In House Impurity
Impurity: Paclitaxel - In House Impurity
CAS Number: 156413-61-5
Possible CAS #: NA
Molecular form.: C₅₉H₇₉NO₁₄Si₂
Appearance: White Solid
Melting Point: >149ºC (dec.)
Mol. Weight: 1082.43
Storage: Refrigerator, under inert atmosphere
Solubility: Chloroform (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Aromatics, Chiral Reagents, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Protected Paclitaxel (P132500). An antineoplastic. Used in the study of structure and function of microtubles into tubulin. Paclitaxel is now used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanced forms of Kaposi’s sarcoma. Paclitaxel is a mitotic inhibitor used in cancer chemotherapy. Paclitaxel - In House Impurity.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:
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