Catalogue number: T700500
Chemical name: TPCA-1
Synonyms: 2-[(Aminocarbonyl)amino]-5-(4-fluorophenyl)-3-thiophenecarboxamide; 5-(4-Fluorophenyl)-2-ureidothiophene-3-carboxylic acid amide; IKK 2 Inhibitor IV; TPCA 1
CAS Number: 507475-17-4
Possible CAS #: NA
Molecular form.: C₁₂H₁₀FN₃O₂S
Appearance: Pale Beige Solid
Melting Point: >217°C (dec.)
Mol. Weight: 279.29
Storage: -20°C Freezer
Solubility: DMSO (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Amines, Aromatics, Heterocycles, Inhibitors, Sulfur & Selenium Compounds
Boiling Point: No Data Available
Applications: TPCA-1 is a direct dual inhibitor for both IKKβ (IKK-2) and STAT3. It inhibits STAT3 phosphorylation, DNA binding, and transactivation in vivo. Synergistic treatment of TPCA-1 with tyrosine kinase inhibitors (TKIs) can potentially be a more effective method for treating cancers.
Dangerous Goods Info: NA
Peer Review Product Citations:
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  Pack size Price(USD)
500µg $40.00
5mg $70.00
50mg $275.00
  Pack size Price(USD)
1mg $50.00
10mg $115.00
100mg $450.00

Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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