Catalogue Number: T444880
Chemical Name: Tipifarnib
Synonyms: 6-[(R)-Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone; (R)-(+)-R 115777; Zarnestra;
CAS Number: 192185-72-1
Molecular Formula: C₂₇H₂₂Cl₂N₄O
Appearance: Off-White to Pale Beige Solid
Melting Point: 211-213°C (dec.)
Molecular Weight: 489.4
Storage: -20˚C Freezer
Solubility: Chloroform, Methanol
Category: Amines, Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Tyrosine Kinase Inhibitors,
Applications: A farnesyltransferase inhibitor. Sensitizes human multiple myeloma cell to proteasome inhibition by blocking degradation of bortezomib(B675700)-induced aggresomes. Also shown to inhibit the growth of myeloid leukemia cell lines and primary leukemia cells by inducing apoptosis and cell-cycle blockage when combined with rapamycin(R124000).

All Products are stable to be shipped at room temperature, unless otherwise specified.
MSDS: T444880.pdf
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  Pack size Price(USD)
1mg $65.00
25mg $375.00
  Pack size Price(USD)
5mg $85.00
50mg $725.00

Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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