T405504 Chemical Structure

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Product Description

Catalogue NumberT405504
Chemical NameL-Threonine-13C4,15N
SynonymsL-Threonine-1,2,3,4-13C4-15N; (S)-Threonine-13C4,15N; 2-Amino-3-hydroxybutyric-13C4-15N Acid; [R-(R*,S*)]-2-Amino-3-hydroxybutanoic-13C4-15N Acid;
CAS Number202468-39-1
Alternate CAS #72-19-5
Molecular Formula13C4H915NO3
AppearanceWhite to Off-White Solid
Melting Point224 - 230°C
Molecular Weight124.08
StorageHygroscopic, Refrigerator, under inert atmosphere
SolubilityMethanol (Very Slightly), Water (Slightly, Sonicated)
Category Building Blocks; Chiral Molecules; Amino Acids; Isotopic Labeled Analogues; Molecular Biology;
ApplicationsL-Threonine-13C4,15N is an isotopically labelled analog of L-Threonine (T405504), an essential amino acid for human development. L-Threonine-13C4,15N can be useful in sampling and profiling of skin metabolites excreted with sweat using hydrogel (agarose) micropatches. It can also be useful in the determination of the arteriovenous muscle protein balance during non-​steady-​state blood and muscle amino acid concentrations.
ReferencesLeMaster, D.M., et al.: J. Biol. Chem., 257, 1224 (1982); Ballevre, O., et al.: Anal. Biochem., 193, 212 (1991); Roufs, J.B., et al.: Med. Hypotheses, 34, 20 (1991); Blin, O., et al.: J. Neurol., 239, 79 (1992); Dutkiewicz, E. P., et al.: Anal. Chem. (Washington, DC, U. S.), 86, 2337 (2014); Katsanos, C. S., et al.: Am. J. Physiol., 289, E1064 (2005)