Catalogue number: T004940
Chemical name: TAK-960
Synonyms: 4-[(9-Cyclopentyl-7,7-difluoro-6,7,8,9-tetrahydro-5-methyl-6-oxo-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]-2-fluoro-5-methoxy-N-(1-methyl-4-piperidinyl)benzamide;
CAS Number: 1137868-52-0
Alternate CAS #: NA
Molecular form.: CH₃₄F₃N₇O₃
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 561.6
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Protein Kinase Inhibitors and Activators,
Boiling Point: No Data Available
Applications: TAK-960 is a potent and selective inhibitor of polo-like kinase 1 (PLK1), a serine/threonine protein kinase involved in key processes during mitosis. TAK-960 has shown activity in several tumor cell lines, including those that express multidrug-resistant protein 1 (MDR1). TAK-960 treatments has shown significant efficacy against multiple tumor xenografts and is a potential chemotherapeutic agent for patients with advanced tumors.
Dangerous Goods Info: NA

All Products are stable to be shipped at room temperature, unless otherwise specified.
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