|Category:||Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Protein Kinase Inhibitors and Activators, Sulfur & Selenium Compounds,|
|Applications:||A novel Aurora B kinase inhibitor with potential antineoplastic activity. It binds to and inhibits the activity of Aurora B, which may result in a decrease in the proliferation of tumor cells that overexpress Aurora B. Aurora B is a positive regulator of mitosis that functions in the attachment of the mitotic spindle to the centromere; the segregation of sister chromatids to each daughter cell; and the separation of daughter cells during cytokinesis.|
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Product Rating ( T004920)
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