Tacrolimus Hydroxy Acid Lithium Salt (Mixture of Diastereomers) DISCONTINUED

Catalogue number: T004140
Chemical name: Tacrolimus Hydroxy Acid Lithium Salt (Mixture of Diastereomers) DISCONTINUED
Synonyms: Lithium (3S,4R,5S,8R,12S,14S,15R,16S,18R,25aS,E)-8-Allyl-5,15,19-trihydroxy-3-((E)-1-((3R,4R)-4-hydroxy-3-methoxycyclohexyl)prop-1-en-2-yl)-14,16-dimethoxy-4,10,12,18-tetramethyl-1,7,20-trioxo-1,3,4,5,6,7,8,11,12,13,14,15,16,17,18,19,20,22,23,24,25,25a-docosahydropyrido[2,1-c][1,4]oxaazacyclodocosine-19-carboxylate
Impurity:
CAS Number: NA
Possible CAS #: NA
Molecular form.: C₄₄H₇₀LiNO₁₃
Appearance: White to Off-White Solid
Melting Point: 114-116°C
Mol. Weight: 827.97
Storage: Amber Vial, -20°C Freezer, Under inert atmosphere
Solubility: Methanol
Stability: No Data Available
Category: Chiral Reagents, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Tacrlimus Lithium Salt is an analogue of Tacrlimus (F370000), an immunosuppressant that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2. Shown to inhibit the activity of FK-506 binding protein, thereby reversing its effects on sarcoplasmic reticulum Ca+2 release.
Dangerous Goods Info: Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g in the package
References:
Peer Review Product Citations:
MSDS: T004140.pdf
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