Sofosbuvir (R)-Phosphate

Catalogue Number: S675615
Chemical Name: Sofosbuvir (R)-Phosphate
Synonyms: (2S)-Isopropyl 2-(((((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate; N-[[P(R),2’R]-2’-Deoxy-2’-fluoro-2’-methyl-P-phenyl-5’-uridylyl]-L-alanine 1-Methylethyl Ester
CAS Number: 1190308-01-0
Molecular Formula: C₂₂H₂₉FN₃O₉P
Appearance: White to Off-White Solid
Melting Point: 76-82°C
Molecular Weight: 529.45
Storage: -20°C Freezer
Solubility: Chloroform (Slightly), DMSO (Slightly), Ethyl Aceatae (Slightly)
Category: Heterocycles, Impurities, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals
Applications: Sofosbuvir (R)-Phosphate is an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2’-deoxy-2’-α-fluoro-β-C-methyluridine-5’-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.

All Products are stable to be shipped at room temperature, unless otherwise specified.
MSDS: S675615.pdf
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  Pack size Price(USD)
1mg $120.00
10mg $995.00
  Pack size Price(USD)
2.5mg $275.00
25mg $2375.00

Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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