Sofosbuvir 3’,5’-Bis-(S)-phosphate

Catalogue number: S675605
Chemical name: Sofosbuvir 3’,5’-Bis-(S)-phosphate
Synonyms: (2S)-Isopropyl 2-(((((2R,3R,4R,5R)-5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-2-((((R)-(((S)-1-isopropoxy-1-oxopropan-2-yl)amino)(phenoxy)phosphoryl)oxy)methyl)-4-methyltetrahydrofuran-3-yl)oxy)(phenoxy)phosphoryl)amino)propanoate
CAS Number: 1337482-17-3
Alternate CAS #: NA
Molecular form.: C₃₄H₄₅FN₄O₁₃P₂
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 798.69
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Heterocycles, Impurities, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Sofosbuvir 3’,5’-Bis-(S)-phosphate is an impurity of PSI-7977 (P839640), a prodrug that is metabolized to the active antiviral agent 2’-deoxy-2’-α-fluoro-β-C-methyluridine-5’-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.
Dangerous Goods Info: NA

All Products are stable to be shipped at room temperature, unless otherwise specified.
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