Selonsertib


Catalogue number: S253800
Chemical name: Selonsertib
Synonyms: 5-(4-Cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methyl-N-[6-[4-(1-methylethyl)-4H-1,2,4-triazol-3-yl]-2-pyridinyl]benzamide; 5-(4-Cyclopropyl-1H-imidazol-1-yl)-2-fluoro-4-methyl-N-{6-[4-(propan-2-yl)-4H-1,2,4-triazol-3-yl]pyridin-2-yl}benzamide; GS 4977; GS 4997;
Impurity:
CAS Number: 1448428-04-3
Alternate CAS #: NA
Molecular form.: C₂₄H₂₄FN₇O
Appearance: Off-White to Pale Yellow Solid
Melting Point: >180°C (dec.)
Mol. Weight: 445.49
Storage: Refrigerator
Solubility: DMSO (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: No Data Available
Boiling Point: No Data Available
Applications: Selonsertib is an apoptosis signal-regulating kinase 1 (ASK1) inhibitor with potential anti-inflammatory, antineoplastic and anti-fibrotic activities. Selonsertib interacts with the catalytic kinase domain of ASK1 and prevents its phosphorylation and activation. As a result, the expression of genes involved in fibrosis, cellular proliferation, and apoptosis are down regulated.
Dangerous Goods Info: NA
References:

All Products are stable to be shipped at room temperature, unless otherwise specified.
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  Pack size Price(USD)
1mg $95.00
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10mg $320.00
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  Pack size Price(USD)
5mg $190.00
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25mg $640.00
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Exact Weight Packaging ($75(USD) / Vial)
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