Catalogue number: S115000
Chemical name: SANT-1
Synonyms: N-[(3,5-Dimethyl-1-phenyl-1H-pyrazol-4-yl)methylene]-4-(phenylmethyl)-1-piperazinamine
CAS Number: 304909-07-7
Alternate CAS #: NA
Molecular form.: C₂₃H₂₇N₅
Appearance: Off-White to Pale Yellow Solid
Melting Point: 108-111°C
Mol. Weight: 373.49
Storage: -20°C Freezer
Solubility: Chloroform (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Inhibitors
Boiling Point: No Data Available
Applications: A potent antagonist of the sonic hedgehog (Shh) signaling pathway (IC50=20nm inShh-LIGHT2 assay an d in Ptch1-/- cells) that acts by binding to smoothened (Smo: KD=1.2 nM), a distant relative of G protein-coupled receptors. In contrast to cyclopamine, SNAT-1 inhibits the activities of both wild type and oncogenic Smo with equal potency (IC50=30nm in SmoA1-LIGHT2 assay).
Dangerous Goods Info: NA

All Products are stable to be shipped at room temperature, unless otherwise specified.
MSDS: S115000.pdf
Keywords: Buy 304909-07-7 | Purchase 304909-07-7 | Order 304909-07-7 | 304909-07-7 supplier | 304909-07-7 manufacturer | 304909-07-7 distributor | 304909-07-7 cost

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  Pack size Price(USD)
1mg $45.00
10mg $110.00
50mg $425.00
  Pack size Price(USD)
5mg $80.00
25mg $285.00
100mg $775.00

Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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