Catalogue number: S083600
Chemical name: SAG
Synonyms: 3-Chloro-N-[trans-4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]- benzo[b]thiophene-2-carboxamide;
CAS Number: 912545-86-9
Possible CAS #: NA
Molecular form.: C₂₈H₂₈ClN₃OS
Appearance: Orange to Red Oil
Melting Point: No Data Available
Mol. Weight: 490.06
Storage: -20°C Freezer
Solubility: Water
Stability: Light Sensitive
Category: Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds,
Boiling Point: No Data Available
Applications: A potent agonist of Hedgehog (Hh) signalling by activating the Smoothened (Smo) protein function. Studies identify novel properties of molecules displaying potential interest in the treatment of various cancers and brain diseases, and demonstrate that Smo is capable of signaling through G15.
Dangerous Goods Info: NA
Peer Review Product Citations:
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