TRC | Details of CAS = , ChemicalName = (5R)-Rupintrivir, synonym = (2E,4S)-4-[[(2R,5R)-2-[(4-Fluorophenyl)methyl]-6-methyl-5-[[(5-methyl-3-isoxazolyl)carbonyl]amino]-1,4-dioxoheptyl]amino]-5-[(3S)-2-oxo-3-pyrrolidinyl]-2-pentenoic Acid;, MolFormula = C₃₁H₃₉FN₄O₇

Catalogue number:	R701690
Chemical name:	(5R)-Rupintrivir
Synonyms:	(2E,4S)-4-[[(2R,5R)-2-[(4-Fluorophenyl)methyl]-6-methyl-5-[[(5-methyl-3-isoxazolyl)carbonyl]amino]-1,4-dioxoheptyl]amino]-5-[(3S)-2-oxo-3-pyrrolidinyl]-2-pentenoic Acid;
Impurity:
CAS Number:	NA
Alternate CAS #:	NA
Molecular form.:	C₃₁H₃₉FN₄O₇
Appearance:	Off-white solid
Melting Point:	138-140˚C
Mol. Weight:	598.66
Storage:	-20˚C Freezer, Under Inert Atmosphere
Solubility:	Chloroform, Methanol
Stability:	No Data Available
Category:	Anti-virals, Chiral Reagents, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point:	No Data Available
Applications:	The 5R-enantiomer of Rupintrivir (R701700). Rupintrivir (formerly AG7088) is an irreversible inhibitor of the human rhinovirus (HRV) 3C protease that has been demonstrated to have in vitro activity against all HRVs tested, consistent with its interaction with a strictly conserved subset of amino acids in the 3C protease.
Dangerous Goods Info:	NA
References:	Arruda, E., et al.: J. Clin. Microbiol., 35, 2864 ( 1997), Dragovich, P., et al.: J. Med. Chem., 42, 1213 (1999), Kaiser, L., et al.: Antivir. Res., 47, 215 (2000), Binford, S., et al.: Antimicrob. Agents Chemother., 49, 619 (2005), Schmidtke, M., et al.: J. Antimicrob. Chemother., 56, 648 (2005), Arden, K., et al.: J. Med. Virol., 78, 1232 (2006),

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