R701012 Chemical Structure

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Product Description

Catalogue NumberR701012
Chemical NameRTI-55-d3 Hydrochloride
Synonyms(1R,2S,3S,5S)-3-(4-Iodophenyl)-8-(methyl-d3)-8-azabicyclo[3.2.1]octane-2-carboxylic Acid Methyl Ester Hydrochloride; [1R-(exo,exo)]-3-(4-Iodophenyl)-8-(methyl-d3)-8-azabicyclo[3.2.1]octane-2-carboxylic Acid Methyl Ester Hydrochloride; RTI 4229-98-d3 Hydrochloride; β-CIT-d3 Hydrochloride;
Alternate CAS #unlabelled: 141899-24-3
Molecular FormulaC16H18D3ClINO2
Molecular Weight424.72
Category Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
ApplicationsLabelled RTI-55. RTI-55 is a semi-synthetic alkaloid that is a cocaine analogue belonging to the phenyltropane group. RTI-55 acts as a dopamine reuptake inhibitor (DRI) with siginificant abuse potential. RTI-55 is used to assess the rate of dopamine neuron degradation in the brains of patients with Parkinson’s disease.
ReferencesFujita, M. et al.: J. Chem. Neuroanat., 7, 13 (1994); Elmer, G.I. et al.: Pharmacol. Biochem. Behav., 53, 911 (1996); Coulter, C.L. et al.: Brain Res., 690, 217 (1995);