Catalogue number: R684000
Chemical name: Roscovitine
Synonyms: (2R)-2-[[9-(1-methylethyl)-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-1-butanol; (R)-2-[[9-(1-methylethyl)-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-1-butanol; 2-(R)-(1-Ethyl-2-hydroxyethylamino)-6-benzylamino-9-isopropylpurine; CYC 202; (R)-Roscovitine; R-Roscovitine; Roscovitin; Seliciclib;
CAS Number: 186692-46-6
Possible CAS #: NA
Molecular form.: C₁₉H₂₆N₆O
Appearance: White Solid
Melting Point: 107-109°C
Mol. Weight: 354.45
Storage: Refrigerator
Solubility: Chloroform, DMSO
Stability: No Data Available
Category: Apoptosis, Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: Roscovitine is a potent and selective inhibitor of cyclin-dependent kinases (CDKs). Roscovitine has been found to produce apoptosis in treated cancerous cells of non-small cell lung cancer (NSCLC) and other cancers. Studies show that Roscovitine displays increased anti-mitotic activity at the G1/S and G2/M phases of the cell cycle. Roscovitine maybe useful in the treatment of non-small cell lung cancer (NSCLC), leukemia, HIV infection, herpes simplex infection, and the mechanisms of chronic inflammation disorders.
Dangerous Goods Info: NA
Peer Review Product Citations:
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  Pack size Price(USD)
500µg $45.00
5mg $85.00
25mg $175.00
  Pack size Price(USD)
1mg $50.00
10mg $125.00
50mg $325.00

Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   Pending QC

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