28-O-Methyl-rapamycin
| Catalogue number: | R124020 |
| Chemical name: | 28-O-Methyl-rapamycin |
| Synonyms: | 23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine Rapamycin Deriv.; |
| Impurity: | |
| CAS Number: | 159351-88-9 |
| Possible CAS #: | NA |
| Molecular form.: | C₅₂H₈₁NO₁₃ |
| Appearance: | White Solid |
| Melting Point: | >102°C (dec.) |
| Mol. Weight: | 928.2 |
| Storage: | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| Solubility: | DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) |
| Stability: | No Data Available |
| Category: | Chiral Reagents, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals |
| Boiling Point: | No Data Available |
| Applications: | 28-O-Methyl-rapamycin is a derivative of Rapamycin (R124000), a triene macrolide antibiotic isolated from Streptomyces hygroscopicus. Name derived from the native word for Easter Island, Rapa’Nui. Used as an immunosuppressant; antirestenotic. Sirolimus (INN/USAN), also known as rapamycin, is an immunosuppressant drug used to prevent rejection in organ transplantation; it is especially useful in kidney transplants. |
| Dangerous Goods Info: | NA |
| References: | |
| MSDS: | R124020.pdf |
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