R124003 Chemical Structure

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1mg
$ 375.000.0
5mg
$ 1700.000.0
10mg
$ 3180.000.0
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R124003

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Product Description

Catalogue NumberR124003
Chemical NameRapamycin-13C,d3 (contains d0) Technical Grade
Synonyms(-)-Rapamycin-13C,d3; AY 22989-13C,d3; Antibiotic AY 22989-13C,d3; Cypher-13C,d3; NSC 226080-13C,d3; RAPA-13C,d3; RPM-13C,d3; Rapammune-13C,d3; Rapamune-13C,d3; SIIA 9268A-13C,d3; Sirolimus-13C,d3; Wy 090217-13C,d3;
Alternate CAS #Unlabelled: 53123-88-9
Molecular FormulaC₅₀¹³CH₇₆D₃NO₁₃
AppearanceWhite to Pale Yellow Solid
Melting Point>109°C (dec.)
Molecular Weight918.18
Storage-20°C, Hygroscopic
SolubilityChloroform (Slightly), Methanol (Slightly)
StabilityHygroscopic
Category Standards; Chiral Molecules; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
ApplicationsLabelled Rapamycin. A triene macrolide antibiotic isolated from Streptomyces hygroscopicus. Name derived from the native word for Easter Island, RapaтАЩNui. Used as an immunosuppressant; antirestenotic.This compound contains aproximately 2% d0.
ReferencesMartel, P.R., et al.: Can. J. Physiol. Pharmacol., 55, 48 (1977), Carlson, R.P., et al.: J. Pharmacol. Exp. Ther., 266, 1125 (1993), Kahan, B.D., et al.: Lancet, 356, 194 (2000), Holmes, D.R., et al.: Circulation, 109, 634 (2004),