R124000 Chemical Structure

All Products are stable to be shipped at room temperature, unless otherwise specified.
Pack SizeQuantityPrice (USD)Sub Total
1mg
$ 45.000.0
5mg
$ 55.000.0
10mg
$ 90.000.0
25mg
$ 145.000.0
50mg
$ 240.000.0
100mg
$ 440.000.0
Exact Weight Packaging
$ 95.000.0
Total$ 0.0
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R124000

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Product Description

Catalogue NumberR124000
Chemical NameRapamycin (>85%)
Synonyms(-)-Rapamycin; AY 22989; Antibiotic AY 22989; Cypher; NSC 226080; RAPA; RPM; Rapammune; Rapamune; SIIA 9268A; Sirolimus; Wy 090217;
CAS Number53123-88-9
Molecular FormulaC₅₁H₇₉NO₁₃
AppearanceWhite to Pale Yellow Solid
Melting Point170 - 173°C
Molecular Weight914.17
Storage-20°C Freezer
SolubilityChloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly, Sonicated)
Category Standards; Chiral Molecules; Enzyme Activators and Inhibitors; Others; Pharmaceutical/API Drug Impurities/Metabolites; Antibotics;
ApplicationsA triene macrolide antibiotic isolated from Streptomyces hygroscopicus. Name derived from the native word for Easter Island, Rapa’Nui. Used as an immunosuppressant; antirestenotic. Sirolimus (INN/USAN), also known as rapamycin, is an immunosuppressant drug used to prevent rejection in organ transplantation; it is especially useful in kidney transplants. It has shown its efficacy against neurodegenerative diseases including Alzheimer's and Parkinson's.
ReferencesMartel, P.R., et al.: Can. J. Physiol. Pharmacol., 55, 48 (1977), Carlson, R.P., et al.: J. Pharmacol. Exp. Ther., 266, 1125 (1993), Kahan, B.D., et al.: Lancet, 356, 194 (2000), Holmes, D.R., et al.: Circulation, 109, 634 (2004),