RAF 265

Catalogue number: R072900
Chemical name: RAF 265
Synonyms: CHIR 265; 1-Methyl-5-[[2-[5-(trifluoromethyl)-1H-imidazol-2-yl]-4-pyridinyl]oxy]-N-[4-(trifluoromethyl)phenyl]-1H-benzimidazol-2-amine
CAS Number: 927880-90-8
Possible CAS #: NA
Molecular form.: C₂₄H₁₆F₆N₆O
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 518.41
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: RAF 265 is a multikinase inhibitor that has displayed BRAF inhibiting activity in clinical trials. It could be used in the treatment of a subpopulation of human melanoma tumors. Has cytotoxic effect of on MDA-MB-231 cells. RAF265 when used with BEZ-235 inhibited ERK, PI3K signaling that reduced growth, proliferation and development of drug resistance in human thyroid cancer cells.
Dangerous Goods Info: NA
Peer Review Product Citations:
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  Pack size Price(USD)
5mg $150.00
25mg $480.00
  Pack size Price(USD)
10mg $240.00
100mg $1440.00

Exact Weight Packaging ($75(USD) / Vial)
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