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| Pack Size | Quantity | Price (USD) | Sub Total |
|---|---|---|---|
| 5mg | $ 205.00 | 0.0 | |
| 50mg | $ 1590.00 | 0.0 | |
| Exact Weight Packaging | $ 95.00 | 0.0 | |
| Total | $ 0.0 | ||
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P840120
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Product Description
| Catalogue Number | P840120 |
| Chemical Name | PU-H71 Hydrate |
| Synonyms | 6-Amino-8-[(6-iodo-1,3-benzodioxol-5-yl)thio]-N-(1-methylethyl)-9H-purine-9-propanamine Hydrate; |
| CAS Number | 1202865-65-3 |
| Alternate CAS # | Free Base: 873436-91-0 |
| Molecular Formula | C₁₈H₂₁IN₆O₂S • xH₂O |
| Molecular Weight | 512.37 |
| Category | Research Tools; |
| Applications | PU-H71 is a potent Hsp90 inhibitor (IC50 = 50 nM). Hsp90 plays a critical role in modulating the activity of many cell signaling proteins and are an attractive target for anti-cancer therapeutics. Studies indicate that Hsp90 inhibitors may serve as potential anti-Parkinson′s disease. |
| References | Gewirth, D.T., et al.: J. Med. Chem., 49, 381 (2006), Taldone, T., et al.: Bioorh. Med. Chem., 17, 2225 (2009), |