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Pack Size | Quantity | Price (USD) | Sub Total |
---|---|---|---|
25mg | $ 65.00 | 0.0 | |
50mg | $ 125.00 | 0.0 | |
100mg | $ 215.00 | 0.0 | |
250mg | $ 400.00 | 0.0 | |
500mg | $ 760.00 | 0.0 | |
1g | $ 1455.00 | 0.0 | |
Exact Weight Packaging | $ 95.00 | 0.0 | |
Total | $ 0.0 |
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P840110
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Product Description
Catalogue Number | P840110 |
Chemical Name | Pteroic Acid (>85%) |
Synonyms | 4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoic Acid; NSC 14972; Pyrofolic acid; p-[(2-Amino-4-hydroxy-6-pteridylmethyl)amino]benzoic Acid; Methotrexate EP Impurity D N-Desmethyl Impurity |
Impurity | Methotrexate EP Impurity D N-Desmethyl Impurity |
CAS Number | 119-24-4 |
Molecular Formula | C₁₄H₁₂N₆O₃ |
Appearance | Light Yellow to Dark Yellow Solid |
Melting Point | >300°C (dec.) |
Molecular Weight | 312.28 |
Storage | Hygroscopic, -20°C Freezer, Under inert atmosphere |
Solubility | Aqueous Base (Slightly), DMSO (Slightly) |
Stability | Hygroscopic |
Category | Standards; Pharmaceutical/API Drug Impurities/Metabolites; |
Applications | Pteroic Acid (Methotrexate EP Impurity D N-Desmethyl Impurity) is a constituent as well as a degradation product of Folic Acid (F680300) formed via enzymatic hydrolysis. has been shown to activate the glutamylation of methotrexate by folylpolyglutamate synthetase. |
References | Vickers, P.J. et al.: Can. J. Biochem. Cell Biol., 63, 777 (1985): Tafolla, W.H. et al.: J. Pharmac. Sci., 70, 1273 (1981); Iwai, K. et al.: J. Butrit. Sci. Vitaminol., 23, 95 (1977); |