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| Pack Size | Quantity | Price (USD) | Sub Total |
|---|---|---|---|
| 25mg | $ 65.00 | 0.0 | |
| 50mg | $ 125.00 | 0.0 | |
| 100mg | $ 215.00 | 0.0 | |
| 250mg | $ 400.00 | 0.0 | |
| 500mg | $ 760.00 | 0.0 | |
| 1g | $ 1455.00 | 0.0 | |
| Exact Weight Packaging | $ 95.00 | 0.0 | |
| Total | $ 0.0 | ||
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P840110
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Product Description
| Catalogue Number | P840110 |
| Chemical Name | Pteroic Acid (>85%) |
| Synonyms | 4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoic Acid; NSC 14972; Pyrofolic acid; p-[(2-Amino-4-hydroxy-6-pteridylmethyl)amino]benzoic Acid; Methotrexate EP Impurity D N-Desmethyl Impurity |
| Impurity | Methotrexate EP Impurity D N-Desmethyl Impurity |
| CAS Number | 119-24-4 |
| Molecular Formula | C₁₄H₁₂N₆O₃ |
| Appearance | Light Yellow to Dark Yellow Solid |
| Melting Point | >300°C (dec.) |
| Molecular Weight | 312.28 |
| Storage | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| Solubility | Aqueous Base (Slightly), DMSO (Slightly) |
| Stability | Hygroscopic |
| Category | Standards; Pharmaceutical/API Drug Impurities/Metabolites; |
| Applications | Pteroic Acid (Methotrexate EP Impurity D N-Desmethyl Impurity) is a constituent as well as a degradation product of Folic Acid (F680300) formed via enzymatic hydrolysis. has been shown to activate the glutamylation of methotrexate by folylpolyglutamate synthetase. |
| References | Vickers, P.J. et al.: Can. J. Biochem. Cell Biol., 63, 777 (1985): Tafolla, W.H. et al.: J. Pharmac. Sci., 70, 1273 (1981); Iwai, K. et al.: J. Butrit. Sci. Vitaminol., 23, 95 (1977); |