Pregnenolone Carbonitrile

Catalogue number: P712240
Chemical name: Pregnenolone Carbonitrile
Synonyms: 3β-Hydroxy-20-oxo-pregn-5-ene-16α-carbonitrile; 16α-Cyanopregnenolone; 3β-Hydroxy-20-oxo-5-pregnen-16α-carbonitrile; 3β-Hydroxy-20-oxopregn-5-ene-16α-carbonitrile; 5-Pregnen-3β-ol-20-one-16α-carbonitrile; PCN; Pregn-5-ene-3β-ol-20-oxo-16α-carbonitrile; Pregnenolone 16α-Carbonitrile; Pregnenolone Carbonitrile; SC 4674; (3S,8S,9S,10R,13S,14S,16R,17S)-17-Acetyl-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-16-carbonitrile
Impurity:
CAS Number: 1434-54-4
Possible CAS #: NA
Molecular form.: C₂₂H₃₁NO₂
Appearance: Off-White to Pale Beige Solid
Melting Point: 221-224°C
Mol. Weight: 341.49
Storage: Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility: DMSO (Slightly), Methanol (Slightly, Heated)
Stability: No Data Available
Category: Activators, Chiral Reagents, Steroids
Boiling Point: No Data Available
Applications: Pregnenolone Carbonitrile is a glucocorticoid receptor antagonist that induces the expression of the CYP3A family of steroid hydroxylases and modulates sterol and bile acid biosynthesis in vivo. Pregnenolone Carbonitrile is an an activator of rat pregnane X receptor (PXR).
HPLC Availibility: Yes      Find COA
Dangerous Goods Info: NA
References:
Peer Review Product Citations:
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