P689396 Chemical Structure

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1mg
$ 205.000.0
2.5mg
$ 420.000.0
5mg
$ 675.000.0
10mg
$ 1010.000.0
Exact Weight Packaging
$ 95.000.0
Total$ 0.0
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P689396

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Product Description

Catalogue NumberP689396
Chemical NamePolymyxin B2 Formate Salt
Synonyms1-[(2S)-4-Amino-2-[(6-methyl-1-oxoheptyl)amino]butanoic acid]polymyxin B1 Formate Salt; N2-(6-Methyl-1-oxoheptyl)-L-2,4-diaminobutanoyl-L-threonyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-D-phenylalanyl-L-leucyl-L-2,4-diaminobutanoyl-L-2,4-diaminobutanoyl-L-threonine (10→4)-lactam Formate Salt
Alternate CAS #34503-87-2
Molecular FormulaC₅₅H₉₆N₁₆O₁₃ • x(HCOOH)
AppearanceWhite to Off-White Solid
Melting Point>138°C (dec.)
Molecular Weight1189.45 + x(46.03)
StorageHygroscopic, -20°C Freezer, Under inert atmosphere
SolubilityMethanol (Slightly), Water (Slightly)
StabilityHygroscopic
Category Standards; Amino Acids/Peptides; Pharmaceutical/API Drug Impurities/Metabolites; Antibotics; Natural Products;
ApplicationsPolymyxin B2 is a cyclic lipopeptide antibiotic. It is a component of Polymyxin B which is used as a last-line treatment for multi-drug resistant gram-negative bacteria.
ReferencesCui, A.-Long, et al.: J. of Med. Chem., 61(5), 1845-1857 (2018); Manchandani, Pooja, et al.: Antimicrob. Agents and Chemotherapy, 60(11), 6980-6982 (2016)