P688250 Chemical Structure

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Pack SizeQuantityPrice (USD)Sub Total
1mg
$ 50.000.0
5mg
$ 65.000.0
10mg
$ 95.000.0
25mg
$ 170.000.0
50mg
$ 325.000.0
100mg
$ 590.000.0
Exact Weight Packaging
$ 95.000.0
Total$ 0.0
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P688250

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Product Description

Catalogue NumberP688250
Chemical NamePonatinib
Synonyms3-(2-Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]benzamide; AP 24534; Iclusig
CAS Number943319-70-8
Molecular FormulaC₂₉H₂₇F₃N₆O
AppearanceOff-White to Pale Beige Solid
Melting Point>175°C (dec.)
Molecular Weight532.56
StorageAmber Vial, Refrigerator, Under inert atmosphere
SolubilityDMSO (Slightly), Methanol (Slightly)
StabilityLight Sensitive
Category Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
ApplicationsPonatinib is a tyrosine kinase inhibitors (TKI) and used to treat chronic myeloid leukemia (CML) (1,2,3). Ponatinib is also used in combination with other drugs, such as forskolin, to combat TKI resistance in patient with CML (3), targeted drug in small-cell lung cancer. Potent FAK inhibitor. FGFR/VEGFR/Bcr-Abl inhibitor It is a COVID19-related research product.
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