Ponatinib


Catalogue number: P688250
Chemical name: Ponatinib
Synonyms: 3-(2-Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]benzamide; AP 24534;
Impurity:
CAS Number: 943319-70-8
Possible CAS #: NA
Molecular form.: C₂₉H₂₇F₃N₆O
Appearance: Off-White to Pale Beige Solid
Melting Point: >175°C (dec.)
Mol. Weight: 532.56
Storage: Amber Vial, Refrigerator, Under inert atmosphere
Solubility: DMSO (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Tyrosine Kinase Inhibitors
Boiling Point: No Data Available
Applications: Ponatinib is a tyrosine kinase inhibitors (TKI) and used to treat chronic myeloid leukemia (CML) (1,2,3). Ponatinib is also used in combination with other drugs, such as forskolin, to combat TKI resistance in patient with CML (3), targeted drug in small-cell lung cancer.
Dangerous Goods Info: NA
References: PMID: 27590270
PMID: 24265264
PMID: 27444277
Peer Review Product Citations:

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  Pack size Price(USD)
1mg $50.00
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10mg $95.00
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50mg $325.00
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  Pack size Price(USD)
5mg $65.00
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25mg $170.00
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100mg $595.00
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Exact Weight Packaging ($75(USD) / Vial)
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Inventory Status:   In Stock



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