PK 11195

Catalogue number: P571500
Chemical name: PK 11195
Synonyms: 1-(2-Chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide; N-Methyl-N-(1-methylpropyl)-1-(2-chlorophenyl)isoquinoline-3-carboxamide; RP 52028;
Impurity:
CAS Number: 85532-75-8
Possible CAS #: NA
Molecular form.: C₂₁H₂₁ClN₂O
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 352.86
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Heterocycles, Chelating Agents & Ligands, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: PK 11195 is a high affinity peripheral benzodiazepine receptor (PBR) ligand. PK 11195 has been shown to regulate protein phosphorylation in rat brain mitochondria under control of Ca2+. PK11195 promotes mitochondrial apoptosis and blocks P-glycoprotein (Pgp)-mediated drug efflux to chemosensitize cancer cells.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:
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  Pack size Price(USD)
5mg $40.00
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25mg $110.00
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  Pack size Price(USD)
10mg $45.00
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50mg $190.00
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Exact Weight Packaging ($75(USD) / Vial)
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