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| Pack Size | Quantity | Price (USD) | Sub Total |
|---|---|---|---|
| 10mg | $ 105.00 | 0.0 | |
| 50mg | $ 135.00 | 0.0 | |
| 100mg | $ 185.00 | 0.0 | |
| 250mg | $ 410.00 | 0.0 | |
| 1g | $ 1455.00 | 0.0 | |
| Exact Weight Packaging | $ 95.00 | 0.0 | |
| Total | $ 0.0 | ||
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P309025
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Product Description
| Catalogue Number | P309025 |
| Chemical Name | ((R)-1-phenyl-3,4-dihydroisoquinolin-2(1H)-yl)((S)-1-phenyl-3,4-dihydroisoquinolin-2(1H)-yl)methanone |
| Synonyms | Solifenacin Impurity D |
| Impurity | Solifenacin EP Impurity D |
| CAS Number | 2216750-52-4 |
| Molecular Formula | C₃₁H₂₈N₂O |
| Appearance | White to Off-White Solid |
| Melting Point | 180 - 183°C |
| Molecular Weight | 444.57 |
| Storage | 4°C |
| Solubility | Chloroform (Sparingly), Ethyl Acetate (Slightly), Methanol (Slightly) |
| Category | Building Blocks; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites; |
| Applications | ((R)-1-phenyl-3,4-dihydroisoquinolin-2(1H)-yl)((S)-1-phenyl-3,4-dihydroisoquinolin-2(1H)-yl)methanone is a possible impurity of solifenacin (S676700) which is a muscarinic M3 receptor antagoinst. Solifenacin is used in treatment of urinary incontinence. |
| References | Ikeda K., et al.: Arch. Pharmacol., 366, 97, (2002); Chapple, C.R., et al.: Br. J. Urol., 93, 303 (2004); Ohtake, A., et al.: Eur. J. Pharmacol., 492, 243 (2004); Brunton, S., et al.: Curr. Med. Res. Opin., 21, 71 (2005); Habb, F., et al.: Eur. Urol. 47, 376 (2005); Payne, C.K., et al.: Drugs, 66, 175 (2006) |