PHA-543613 Dihydrochloride

Catalogue Number: P294400
Chemical Name: PHA-543613 Dihydrochloride
Synonyms: N-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxamide Dihydrochloride; PHA 543613E;
CAS Number: 478148-58-2
Alternate CAS #: free base: 478149-53-0
Molecular Formula: C₁₅H₁₉Cl₂N₃O₂
Appearance: Tan Solid
Melting Point: >300˚C
Molecular Weight: 344.24
Storage: Refrigerator
Solubility: DMSO, Methanol
Category: Amines, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals, Pfizer compounds
Applications: PHA-543613 is a potent selective α7 nAChR agonist. Nicotinic acetylcholine receptors are ligand-gated ion channels activated by nicotine, expressed in multiple tissues, with high functional expression in brain. The homomeric subtype α7 is a potential therapeutic target for cognitive deficits in schizophrenia and Alzheimer′s disease. PHA-543613 is active in both in vitro (binding, calcium flux, patch-clamp) and in vivo (auditory gating, novel object recognition) assays.

All Products are stable to be shipped at room temperature, unless otherwise specified.
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  Pack size Price(USD)
5mg $85.00
25mg $320.00
100mg $995.00
  Pack size Price(USD)
10mg $150.00
50mg $545.00

Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   Pending QC

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