P132504 Chemical Structure

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Product Description

Catalogue NumberP132504
Chemical NamePaclitaxel-13C6
SynonymsAbraxane-13C6; Genaxol-13C6; Genetaxyl-13C6; OncoGel-13C6; Onxal-13C6; Pacliex-13C6; (-)-Paclitaxel-13C6; Taxol-13C6; Yewtaxan-13C6; NSC 125973-13C6;
Alternate CAS #Unlabelled: 33069-62-4
Molecular FormulaC₄₁¹³C₆H₅₁NO₁₄
AppearanceWhite to Pale Yellow Solid
Molecular Weight859.86
Storage-20°C Freezer
SolubilityChloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
Category Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
ApplicationsPaclitaxel-13C is the labeled analogue of Paclitaxel (P132500). Paclitaxel is an antineoplastic. Used in the study of structure and function of microtubles into tubulin. Paclitaxel is now used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanced forms of Kaposi's sarcoma. Paclitaxel is a mitotic inhibitor used in cancer chemotherapy.
ReferencesLetourneau, P.C., et al.: J. Cell Biol., 98, 1355 (1984), Manfredi, J.J., et al.: Pharmacol. Ther., 25, 83 (1984), Danesi, R., et al.: Mol. Pharmacol., 47, 1106 (1995), Markman, M., et al.: Expert. Opin. Pharmacother., 3, 755 (2002), Stone, G.W., et al.: N. Engl. J. Med., 350, 221 (2004),