O714502 Chemical Structure

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$ 200.000.0
$ 1545.000.0
Exact Weight Packaging
$ 145.000.0
Total$ 0.0
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Product Description

Catalogue NumberO714502
Chemical NameOuabain-d3 (Major)
Synonyms(1β,3β,5β,11α)-3-[(6-Deoxy-α-L-mannopyranosyl)oxy]-1,5,11,14,19-pentahydroxycard-20(22)-enolide-d3; g-Strophanthin-d3;
Alternate CAS #unlabelled: 630-60-4
Molecular FormulaC₂₉H₄₁D₃O₁₂
AppearanceWhite to Off-White Solid
Melting Point185-188°C
Molecular Weight587.67
Storage4°C, Hygroscopic
SolubilityMethanol (Slightly), Water (Slightly)
Category Building Blocks; Steroids; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; Carbohydrates and Oligosaccharides;
ApplicationsLabelled Ouabain (O714500). A cardiac glycoside that inhibits Na(+)/K(+) ATPase. It regulates transcription of MDR (increase, Pgp) and MRP (increase MRP1 and decrease CFTR, cyctic fibrosis transport receptor or cAMP-activated Cl- channel) genes, also alters localization of MRP1.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
ReferencesPadilha, A.S. et al.: Clin. Exp. Pharmacol. Physiol., 35, 801 (2008); Blaustein, M.P. et al.: Clin. Exp. Hypertens. 20, 691 (1998); van Huysse, J.W. et al.: Clin. Exp. Hypertens. 20, 657 (1998);