NSC 109555
| Catalogue Number: | N900530 |
| Chemical Name: | NSC 109555 |
| Synonyms: | 4,4’-Diacetyldiphenylurea bis(guanylhydrazone) Bismethanesulfonate; 2,2’-[Carbonylbis(imino-4,1-phenyleneethylidyne)]bis-hydrazinecarboximidamide Dimethanesulfonate |
| CAS Number: | 15427-93-7 |
| Molecular Formula: | C₂₁H₃₂N₁₀O₇S₂ |
| Molecular Weight: | 600.67 |
| Category: | Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals |
| Applications: | NSC 109555 is an inhibitor of checkpoint kinase 2 (Chk2), a serine/threonine kinase involved in the ATM-Chk2 checkpoint pathway. Drugs that target Chk2 in combination with DNA-damaging agents can be beneficial in cancer therapy. Studies in mice, rats, rabbits, dogs, and monkeys have shown that NSC 109555 displays toxic effects. A singe injection of the drug at a concentration of 12.5-25 mg/kg caused acute paralysis leading to apnea and death. |
| References: | |
|
All Products are stable to be shipped at room temperature, unless otherwise specified. |
|
| Product Rating |
✖ Product Rating ( N900530)Fill out the feedback form to helo us improve |
Keywords: Buy 15427-93-7 | Purchase 15427-93-7 | Order 15427-93-7 |
15427-93-7 supplier | 15427-93-7 manufacturer | 15427-93-7 distributor | 15427-93-7 cost
