1,4-O-Didesmethyl rac-Niranthin

Catalogue number: N480990
Chemical name: 1,4-O-Didesmethyl rac-Niranthin
Synonyms:
Impurity:
CAS Number: 81263-83-4
Possible CAS #: NA
Molecular form.: C??H??O?
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 404.45
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: 1,4-O-Didesmethyl rac-Niranthin is an intermediate in the synthesis of rac-Niranthin (N481000), a lignan compound isolated from the plant Phyllanthus amarus and shows anti-leishmanial activity. It acts through induction of topoisomerase I-mediated DNA-protein adduct formation in Leishmania cells triggering apoptosis of cellular nucleases. It also maintains the ability to reduce uric acid concentrations through xanthine oxidase inhibition.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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