N465303 Chemical Structure

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1mg
$ 305.000.0
10mg
$ 2935.000.0
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N465303

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Product Description

Catalogue NumberN465303
Chemical NameNilotinib-d6
Synonyms4-Methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]benzamide-d6; AMN 107-d6; Tasigna-d6;
CAS Number1268356-17-7
Alternate CAS #Unlabelled: 641571-10-0
Molecular FormulaC₂₈H₁₆D₆F₃N₇O
AppearanceOff-White to Light Beige Solid
Melting Point>187ºC (dec.)
Molecular Weight535.55
StorageRefrigerator
SolubilityDMSO (Slightly), Methanol (Slightly, Heated)
Category Building Blocks; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
ApplicationsNilotinib-d6, is the labeled analogue of Nilotinib (N465300), which might be useful in treatment of chronic myelogenous leukemia. It is a COVID19-related research product.
ReferencesCorbin, A., et al.: J. Biol. Chem., 277, 32214(2002), Golemovic, M., et al.: Clin. Cancer Res., 11, 4941 (2005), Gleixner, K., et al.: Blood, 107, 752 (2006), Nicolini, F., et al.: Leukemia, 20, 1061 (2006),