N385745 Chemical Structure

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Pack SizeQuantityPrice (USD)Sub Total
50mg
$ 170.000.0
250mg
$ 790.000.0
500mg
$ 1360.000.0
Exact Weight Packaging
$ 95.000.0
Total$ 0.0
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N385745

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Product Description

Catalogue NumberN385745
Chemical Name(+)-Nefopam Hydrochloride
Synonyms(S)-3,4,5,6-Tetrahydro-5-methyl-1-phenyl-1H-2,5-benzoxazocine Hydrochloride; (1S)-3,4,5,6-Tetrahydro-5-methyl-1-phenyl-1H-2,5-benzoxazocine Hydrochloride; S-Nefopam Hydrochloride
CAS Number53648-31-0
Alternate CAS #110011-82-0
Molecular FormulaC₁₇H₁₉NO • HCl
AppearancePale Red to Light Red Solid
Melting Point189 - 187°
Molecular Weight253.34 + 36.46
Storage4°C
SolubilityDMSO (Sparingly), Water (Slightly)
Category Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
Applications(+)-Nefopam inhibits the uptake of 5-hydroxytryptamine (5-HT), noradrenaline and dopamine in synaptosomal preparations from rat forebrain, hippocampus and striatum. A cyclized analog of orphenadrine and diphenhydramine; representative of a new class of centrally acting skeletal muscle relaxants, the benzoxazocines. Analgesic; antidepressant.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
ReferencesRosland, J. H., et al.: J. Pharm. Pharmacol, 42, 437 (1990); Bassett, et al.: Br. J. Pharmacol., 37, 69 (1969), Klohs, et al.: Arzneim.-Forsch., 22, 132 (1972), Hell, et al.: Drugs, 19, 249 (1980),