N379800 Chemical Structure

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1mg
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10mg
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N379800

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Product Description

Catalogue NumberN379800
Chemical NameNaxagolide Hydrochloride
Synonyms(4aR-trans)-3,4,4a,5,6,10b-Hexahydro-4-propyl-2H-naphth[1,2-b]-1,4-oxazin-9-ol Hydrochloride; (+)-Propyl-9-hydroxynaphthoxazine Hydrochloride; L 647339; MK 458;(+)-PHNO Hydrochloride; Dopazinol Hydrochloride; Nazagolide HCl;
CAS Number99705-65-4
Alternate CAS #Free Base: 88058-88-2
Molecular FormulaC₁₅H₂₂ClNO₂
AppearanceOff-White to Pale Orange Solid
Melting Point>260°C (dec.)
Molecular Weight283.79
StorageRefrigerator
SolubilityDMSO (Slightly), Methanol (Slightly), Water (Slightly)
Category Standards; Chiral Molecules; Neurochemicals; Pharmaceutical/API Drug Impurities/Metabolites;
ApplicationsA dopamine D2-receptor agonist. Used for treatment of extrapyramidal disorders. Antiparkinsonian drug.
ReferencesFujita, N., et al.: Brain Res., 333, 231 (1985), Weiss, F., et al.: Eur. J, Pharmacol., 337, 219 (1997), Wilson, A., et al.: J. Med. Chem., 48, 4153 (2005), Ginovart, N., et al.: J. Neurochem., 97, 1089 (2006), Willeit, M., et al.: Biol. Psychiatry, 59, 389 (2006),