Catalogue number: M425030
Chemical name: MK-2048
Synonyms: (6S)-2-(3-Chloro-4-fluorobenzyl)-8-ethyl-10-hydroxy-N,6-dimethyl-1,9-dioxo-1,2,6,7,8,9-hexahydropyrazino[1’,2’:1,5]pyrrolo[2,3-d]pyridazine-4-carboxamide;
CAS Number: 869901-69-9
Possible CAS #: NA
Molecular form.: C₂₁H₂₁ClFN₅O₄
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 461.87
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: MK-2048 represents a prototype second generation integrase strand transfer inhibitor (INSTI), it was developed with the goal of retaining activity against viruses containing mutations assiciated with resistance of first-generation INSTIs, raltegravir (R100312). MK-2048 exhibits inhibitory activity towards HIV integrase and towards HIV replication. It is four times more effective in inhibiting HIV enzyme integrase than the first generation inhibitor, raltegravir.
Dangerous Goods Info: NA
Peer Review Product Citations:
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  Pack size Price(USD)
5mg $225.00
50mg $1000.00
  Pack size Price(USD)
10mg $350.00
200mg $2250.00

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