L-Methionine [R,S]-Sulfoximine


Catalogue Number: M260500
Chemical Name: L-Methionine [R,S]-Sulfoximine
Synonyms: L-S-[3-Amino-3-carboxypropyl]-S-methyl-[R,S]-sulfoximine; (2S)-2-Amino-4-(S-methylsulfonimidoyl)butanoic Acid;
CAS Number: 15985-39-4
Molecular Formula: C₅H₁₂N₂O₃S
Appearance: White to Off-White Solid
Melting Point: >210°C (dec.)
Molecular Weight: 180.23
Storage: -20°C Freezer
Solubility: Formic Acid, Water
Category: Amino Acids & Derivatives, Sulfur & Selenium Compounds
Applications: Methionine sulfoximine inhibits both glutamine synthetase and g-glutamylcysteine synthetase. Working concentrations for inhibition of g-glutamylcysteine synthetase are 0.2-2.0 mM (52% inhibition occured at 100 mM). Methionine sulfoximine is also a toxic byproduct of nitrogen trichloride, a compound that was used to bleach unprocessed wheat flour prior to 1968. The compound has been investigated as a potential neurotoxin linked to diseases such as amyotrophic lateral sclerosis (ALS) and Parkinson’s disease.
References:

All Products are stable to be shipped at room temperature, unless otherwise specified.
MSDS: M260500.pdf
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1g $150.00
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500mg $55.00
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5g $375.00
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Exact Weight Packaging ($75(USD) / Vial)
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