Catalogue Number: M253000
Chemical Name: 2-Mercapto-L-histidine
Synonyms: (αS)-α-Amino-2,3-dihydro-2-thioxo-1H-Imidazole-4-propanoic Acid; 2-Thiolhistidine 1H-Imidazole-4-propanoic Acid; L-2-Mercaptohistidine; L-2-Thiolhistidine; L-Thiohistidine;
CAS Number: 2002-22-4
Molecular Formula: C₆H₉N₃O₂S
Appearance: Off-White Solid
Melting Point: >250°C (dec.)
Molecular Weight: 187.22
Storage: -20°C Freezer
Solubility: Aqueous Acid (Slightly)
Category: Amino Acids & Derivatives, Heterocycles, Sulfur & Selenium Compounds
Applications: An intermediate in the formation of L-egothioneine, a natural amino acid ubiquitously present in cells and tissues of most plants and mammalian species. In humans, L-ergothioneine is found in red blood cells, liver, kidney, brain, seminal fluid, and cataract-free lenses at concentrations ranging from 100 uM to 2 mM. L-ergothioneine is exclusively biosynthesized in fungi and mycobacteria. Hence, humans assimilate it through dietary intake. L-ergothioneine has been proven to act as an antioxidant in vivo and to afford protection from g and UV radiation as well as from singlet oxygen in vivo. Recently, it has been shown that L-ergothioneine protects isolated perfused heart against the deleterious effect of post-ischemic reperfusion. The intermediate, 2-mercaptohistine has been used for the

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MSDS: M253000.pdf
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