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| Pack Size | Quantity | Price (USD) | Sub Total |
|---|---|---|---|
| 1mg | $ 140.00 | 0.0 | |
| 10mg | $ 1100.00 | 0.0 | |
| Exact Weight Packaging | $ 75.00 | 0.0 | |
| Total | $ 0.0 | ||
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M219023
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Product Description
| Catalogue Number | M219023 |
| Chemical Name | (2R,5S)-L-Menthol-5-(4-amino-2-oxo-1(2H)-pyrimidinyl-13C)-1,3-oxathiolane-2-carboxylate |
| Synonyms | (2R,5S)-5-(4-Amino-2-oxo-1(2H)-pyrimidinyl-13C)-1,3-oxathiolane-2-carboxylic Acid (1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexyl Ester |
| Alternate CAS # | Unlabelled: 147027-10-9 |
| Molecular Formula | C₁₇¹³CH₂₇N₃O₄S |
| Molecular Weight | 382.48 |
| Category | Building Blocks; Isotopic Labeled Analogues; |
| Applications | (2R,5S)-L-Menthol-5-(4-amino-2-oxo-1(2H)-pyrimidinyl-13C)-1,3-oxathiolane-2-carboxylate is a labeled analogue of (2R,5S)-L-Menthol-5-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylate (M219020), an intermediate in the synthesis of Lamivudine (L172500), a potent nucleoside reverse transcriptase inhibitor. Antiviral. Lamivudine has been used for treatment of chronic hepatitis B. |
| References | Chang, C., et al.: J. Biol. Chem., 267, 13938 (1992); Jeong, L., et al.: J. Med. Chem., 36, 181 (1993); Morris, D.M., J. Pharm. Biomed. Anal., 12, 255 (1944); Nevens, B.F., et al.: Gastroenterology, 113, 1258 (1997); Perry, C.M., et al.: Drugs, 53, 657 (1977) |