MDV 3100
| Catalogue number: | M199800 |
| Chemical name: | MDV 3100 |
| Synonyms: | 4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluoro-N-methylbenzamide; MDV3100; MDV-3100; Enzalutamide; |
| Impurity: | |
| CAS Number: | 915087-33-1 |
| Possible CAS #: | NA |
| Molecular form.: | C₂₁H₁₆F₄N₄O₂S |
| Appearance: | White Solid |
| Melting Point: | 198-200°C |
| Mol. Weight: | 464.44 |
| Storage: | Refrigerator |
| Solubility: | DMSO (Slightly), Methanol (Slightly) |
| Stability: | No Data Available |
| Category: | Apoptosis, Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds, |
| Boiling Point: | No Data Available |
| Applications: | MDV 3100 is an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex. MDV 3100 has also been shown to induce tumor cell apoptosis, and has no agonist activity. MDV 3100 is a candidate for the treatment of castration-resistant prostate cancer. |
| Dangerous Goods Info: | NA |
| References: | |
| Peer Review Product Citations: | |
| MSDS: | M199800.pdf |
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