MCOPPB Trihydrochloride
| Catalogue number: | M199500 |
| Chemical name: | MCOPPB Trihydrochloride |
| Synonyms: | 1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-(3R)-3-piperidinyl-1H-benzimidazole TriHydrochloride; PF-01678059; |
| Impurity: | |
| CAS Number: | 1108147-88-1 |
| Possible CAS #: | NA |
| Molecular form.: | C₂₆H₄₃Cl₃N₄ |
| Appearance: | White Solid |
| Melting Point: | >249°C (dec.) |
| Mol. Weight: | 518.01 |
| Storage: | No Data Available |
| Solubility: | Chloroform, Methanol |
| Stability: | No Data Available |
| Category: | Agonists, Aromatics, Heterocycles, Neurochemicals, Pfizer Compounds, Pharmaceuticals, Intermediates & Fine Chemicals, |
| Boiling Point: | No Data Available |
| Applications: | A potent non-peptide nociceptin/orphanin FQ peptide (NOP)-receptor full agonist [or opioid-receptor-like-1 (ORL1) receptor agonist]. It is the most potent, non-peptide NOP full agonists in vitro and a potent anxiolytic in the mice. It inhibited signaling through the NOP receptor in the mouse brain, suggesting that it penetrated into the brain after it was orally administered. It did not affect locomotor activity or memory, nor did it contribute to ethanol-induced hypnosis. |
| Dangerous Goods Info: | NA |
| References: | |
| Peer Review Product Citations: | |
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