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| Pack Size | Quantity | Price (USD) | Sub Total |
|---|---|---|---|
| 1mg | $ 50.00 | 0.0 | |
| 5mg | $ 90.00 | 0.0 | |
| 10mg | $ 155.00 | 0.0 | |
| 100mg | $ 1300.00 | 0.0 | |
| Exact Weight Packaging | $ 95.00 | 0.0 | |
| Total | $ 0.0 | ||
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- Ships On : 5/23/2022
M199500
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Product Description
| Catalogue Number | M199500 |
| Chemical Name | MCOPPB Trihydrochloride |
| Synonyms | 1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-(3R)-3-piperidinyl-1H-benzimidazole TriHydrochloride; PF-01678059; |
| CAS Number | 1108147-88-1 |
| Alternate CAS # | freeamine: 1028969-49-4 |
| Molecular Formula | C₂₆H₄₃Cl₃N₄ |
| Appearance | White Solid |
| Melting Point | >249°C (dec.) |
| Molecular Weight | 518.01 |
| Solubility | Chloroform, Methanol |
| Category | Standards; Pharmaceutical/API Drug Impurities/Metabolites; |
| Applications | A potent non-peptide nociceptin/orphanin FQ peptide (NOP)-receptor full agonist [or opioid-receptor-like-1 (ORL1) receptor agonist]. It is the most potent, non-peptide NOP full agonists in vitro and a potent anxiolytic in the mice. It inhibited signaling through the NOP receptor in the mouse brain, suggesting that it penetrated into the brain after it was orally administered. It did not affect locomotor activity or memory, nor did it contribute to ethanol-induced hypnosis. |
| References | Hayashi, S. et al.: J. Med. Chem., 52, 610 (2009); Hirao, A. et al.: J . Pharmacol. Sci., 106, 361 (2008); |