L488772 Chemical Structure

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Product Description

Catalogue NumberL488772
Chemical NameLysipressin-d2 Trifluoroacetic Acid Salt
Synonyms19-Amino-4-[2-[[5-amino-1-[(carbamoylmethyl)carbamoyl]pentyl]carbamoyl]-1-pyrrolidinylcarbonyl]-13-benzyl-7-(carbamoylmethyl)-16-p-hydroxybenzyl-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloeicosane-10-propionamide-d2 Trifluoroacetic Acid Salt; 1,2-Dithia-5,8,11,14,17-pentaazacycloeicosane, cyclic peptide deriv.-d2 Trifluoroacetic Acid Salt; 3-(Phenylalanine)-8-lysine Oxytocin-d2 Trifluoroacetic Acid Salt; 8-L-Lysine Vasopressin-d2 Trifluoroacetic Acid Salt; Diapid-d2 Trifluoroacetic Acid Salt; L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-lysyl-glycinamide-d2 Cyclic (1→6)-Disulfide; L-Lysine Vasopressin-d2; Lypressin-d2 Trifluoroacetic Acid Salt; Lysine Pitressin-d2 Trifluoroacetic Acid Salt; Lysine Vasopressin-d2 Trifluoroacetic Aci
Alternate CAS #Unlabelled: 50-57-7
Molecular FormulaC46H63D2N13O12S2 • x(C2HF3O2)
AppearanceWhite Solid
Melting Point>155ºC (dec.)
Molecular Weight1058.23 + x(114.02)
StorageHygroscopic, Refrigerator, under inert atmosphere
SolubilityAqueous Acid (Slightly), Water (Slightly)
Category Standards; Amino Acids; Isotopic Labeled Analogues; Amino Acids/Peptides; Pharmaceutical/API Drug Impurities/Metabolites;
ApplicationsIsotope labelled Lysipressin (L488770) is an analog of Vasopressin (A769550), a powerful vasopressor used to modulate blood pressure. An endogenous antidiuretic hormone in most mammalian species. It is released into the blood from nerve terminals in the posterior pituitary and median eminence. It is a neurotransmitter in the central nervous system and also implicated in a variety of physiological processes such as regulating water balance by antidiuretic action.
ReferencesPerucca, J. et al.: J. AM. Soc. Nephrol., 19, 1721 (2008); Toba, K. et al.: Prog. Brain Res., 119, 337 (1998); Berrada, K. et al.: J. Biol. Chem., 275, 27229 (2000);