Lonafarnib


Catalogue number: L469445
Chemical name: Lonafarnib
Synonyms: 4-[2-[4-[(11R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]-1-piperidinyl]-2-oxoethyl]-1-piperidinecarboxamide; Sarasar; Sch 66336;
Impurity:
CAS Number: 193275-84-2
Alternate CAS #: NA
Molecular form.: C₂₇H₃₁Br₂ClN₄O₂
Appearance: White to Off-White Solid
Melting Point: 150-152°C
Mol. Weight: 638.82
Storage: Refrigerator
Solubility: Chloroform (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: Lonafarnib is an orally bioavailable tricyclic inhibitor of farnesyl protein transferase. It inhibits Rheb farnesylation and mTOR signaling and enhances taxane and tamoxifen antitumor activity. Studies show that it induces CCAAT/enhancer-binding protein homologous protein-dependent expression of death receptor 5, leading to induction of apoptosis in human cancer cells
Dangerous Goods Info: NA
References:

All Products are stable to be shipped at room temperature, unless otherwise specified.
MSDS: L469445.pdf
Product Rating
Keywords: Buy 193275-84-2 | Purchase 193275-84-2 | Order 193275-84-2 | 193275-84-2 supplier | 193275-84-2 manufacturer | 193275-84-2 distributor | 193275-84-2 cost

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  Pack size Price(USD)
1mg $50.00
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10mg $110.00
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50mg $375.00
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  Pack size Price(USD)
5mg $65.00
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25mg $220.00
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100mg $675.00
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Exact Weight Packaging ($75(USD) / Vial)
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Inventory Status:   In Stock




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